Aromasin (Exemestane) 25mg is a suicidal aromatase inhibitor that permanently deactivates the aromatase enzyme, preventing testosterone from converting to oestrogen. Unlike Arimidex (which temporarily binds to the enzyme and can cause oestrogen rebound), Aromasin destroys the enzyme entirely. New aromatase must be produced by the body, providing more stable oestrogen control.
When You Need Aromasin
Any steroid that aromatises (converts to oestrogen) can cause water retention, bloating, elevated blood pressure, and gynecomastia. This includes Testosterone (all esters), Dianabol, and Deca-Durabolin. Aromasin prevents these side effects by reducing circulating oestrogen levels.
Suggested Protocol
- On-cycle dose: 12.5mg every other day (standard). Adjust based on bloodwork
- High-aromatising cycles (Dbol + Test): 25mg every other day
- Take with a fat source (meal with fats) to improve absorption by up to 40%
- Monitor oestrogen via bloodwork. Crashing oestrogen too low causes joint pain, fatigue, and low mood
Aromasin vs Arimidex
- Aromasin: suicidal AI (permanent enzyme deactivation). No oestrogen rebound. Mildly beneficial for lipids
- Arimidex: competitive AI (temporary binding). Possible oestrogen rebound if discontinued suddenly. Slightly harsher on lipids
Key Facts
- Class: Steroidal aromatase inhibitor (suicidal)
- Half-life: 24 hours
- Oestrogen reduction: approximately 85% at 25mg/day
For side-effect management across all compounds, read our Steroid Side Effects Guide. See also: Arimidex.



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